CrazyTalk Animator Pipeline can be used for creating 2D animation. You can add any photo to the program to create talking characters. Even though the program is not a 3D modelling tool, it can create some 3D motion effect for the characters - this is only present in the Pipeline version. You will also be able to work with motion captured data and BVH or FBX files generated from Maya, Motion Builder, or any other 3D tools.
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